崔柏，博士，副教授，硕士生导师。主持国家自然科学青年基金和面上基金；近5年在Cell Metabolism, Journal of Clinical Investigation, Cell Research，Brain Behav Immun等期刊发表SCI论文多篇。现任第九届中国病理生理学会免疫专业委员会青年委员，中国抗癌协会肿瘤节律专委会委员。

研究方向

身心行为与肿瘤节律异常调控和治疗策略

项目情况

1. 国家自然科学基金，面上项目，慢性压力通过ALKBH5重塑m6A修饰促进肺癌干性的机制研究

2. 国家自然科学基金，青年项目，慢性压力通过上调脂肪酸合成酶FASN促进肺癌细胞干性特征的分子机制研究

3. 辽宁省自然科学基金，青年科技人才“育苗” 项目，慢性压力释放肾上腺素上调ACSS2促进乳腺癌细胞干性特征的分子机制研究

4. 大连市高层次人才创新支持计划，青年科技之星，慢性压力促进乳腺癌细胞干性特征的糖代谢靶点筛选及干预

代表性发表

1. Fei Peng#, Jinxin Lu#, Keyu Su#, Xinyu Liu, Huandong Luo, Bin He, Cenxin Wang, Xiaoyu Zhang, Fan An, Dekang Lv, Yuanyuan Luo, Qitong Su, Tonghui Jiang, Ziqian Deng, Bin He, Lingzhi Xu, Tao Guo, Jin Xiang, Chundong Gu, Ling Wang, Guowang Xu, Ying Xu, Mindian Li, Keith W. Kelley, Bai Cui* and Quentin Liu*. Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis. Cell Metab. 2024 May 14:S1550-4131(24)00138-4. 

2. Peng F#, Xu J#*, Cui B#, Liang QL#, Zeng S#, He B#, Zou H, Li MM, Zhao H, Meng YT, Chen J, Liu B, Lv SS, Chu P, An F, Wang ZF, Huang JX, Zhan YJ, Liao YW, Lu JX, Xu LZ, Zhang J, Sun ZL, Li ZG, Wang FJ, Lam EW and Liu Q*. Oncogenic AURKA-enhanced N6-methyladenosine Modification Increases DROSHA mRNA Stability to Transactivate STC1 in Breast Cancer Stem-like Cells. Cell Res. 2021 Mar;31(3):345-361.

3. Bai Cui#, Fei Peng#, Jinxin Lu#, Bin He, Qitong Su, Huandong Luo, Ziqian Deng, Tonghui Jiang, Keyu Su, Yanping Huang, Zaheer ud Din, Eric W.-F. Lam, Keith W. Kelley*, Quentin Liu*. Cancer and stress: NextGen strategies. Brain Behav Immun. 2021 Mar; 93:368-383.

4. Cui B#, Luo Y#, Tian P#, Peng F#, Lu J#, Yang Y#, Su Q, Liu B, Yu J, Luo X, Yin L, Cheng W, An F, He B, Liang D, Wu S, Chu P, Song L, Liu X, Luo H, Xu J, Pan Y, Wang Y, Li D, Huang P, Yang Q, Zhang L, Zhou BP, Liu S, Xu G, Lam EW, Kelley KW, Liu Q*. Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells. J Clin Invest. 2019 Mar 1;129(3):1030-1046

5. Jinxin Lu^#, Xiaoyu Zhang^#, Keyu Su^#, Huandong Luo^#, Congcong Liu, Yuqing Yang, Bin He, Cenxin Wang, Zhuoran Zhao, Xianxian Liu, Xu Wang, Peixuan Meng, Dekang Lv, Chunli Wang, Keith W. Kelley, Ling Wang*, Bai Cui*, Quentin Liu* and Fei Peng*. Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress. Cell Commun Signal. 2024 Jul 25;22(1):375

联系方式

cuibaila@163.com